Mechanisms of Heavy Menstrual Bleeding

Grant number: 1008553 | Funding period: 2011 - 2013

Completed

Abstract

Excessive menstrual bleeding (menorrhagia) affects the health and quality of life of 1 in 3 women. There are also significant economic issues due to treatment costs and absence from work. Current medical therapies are insufficient or associated with side-effects and many women instead choose surgery (hysterectomy). The overall aim of our research is to elucidate the molecular mechanisms responsible for heavy menstrual bleeding and to determine how medical therapies can be better directed at individual women.

Related publications (2)

Differential Gene Expression in Menstrual Endometrium from Women with Self-Reported Heavy Menstrual Bleeding

JE Girling, MG Lockhart, M Olshansky, P Paiva, N Woodrow, JL Marino, M Hickey, PAW Rogers

2017-01-01

Heavy menstrual bleeding (HMB) is a significant social and public health issue for menstruating women. Development of targeted tre..

Identification of genes differentially expressed in menstrual breakdown and repair

P Paiva, MG Lockhart, JE Girling, M Olshansky, N Woodrow, JL Marino, M Hickey, PAW Rogers

2016-12-01

STUDY QUESTION: Does the changing molecular profile of the endometrium during menstruation correlate with the histological profile..

University of Melbourne Researchers

Martha Hickey

Peter Rogers